So, my computer was being really, really slow this morning. After checking Task Manager to see what was going on, I noticed one process was consuming WAY too much CPU time, so I killed it (it was a service host, something that you really aren't supposed to kill). Anyway...I killed it and was promptly disconnected from my remote desktop session ('cause I typically only use my desktop by remoting into it from work or my laptop at home). I physically logged onto the computer and decided that, since it had been about a month, it was time for a reboot. As I commonly do when rebooting, I checked for updates, and there were 10 waiting to be installed (yeah--I don't update often).
Long story short, ran the update, rebooted, logged in, started Outlook...or rather, tried to start Outlook. "Windows cannot find MAPI32.DLL...blah, blah, blah." One of the updates was for Office 2007, and I've seen this happen with previous versions of Office, too. Very annoying... I ran a repair on the Office install, and an hour-and-a-half later, Outlook is working again. Funny that it takes 1.5 hours to repair but only 30 minutes to install.